HIV Dynamics with a Trilinear Antibody Growth Function and Saturated Infection Rate

Abstract

The objective of this paper is to study a new mathematical model describing the human immunodeficiency virus (HIV). The model incorporates the impacts of cytotoxic T lymphocyte (CTL) immunity and antibodies with trilinear growth functions. The boundedness and positivity of solutions for non-negative initial data are proved, which is consistent with biological studies. The local stability of the equilibrium is established. Finally, numerical simulations are presented to support our theoretical findings.

Keywords

• antibody response
• CTL response
• HIV infection
• numerical simulation
• viral dynamics