Journal of Diabetes Research (Jan 2020)

Association between Serum Ferritin and Blood Lipids: Influence of Diabetes and hs-CRP Levels

  • Lianlong Yu,
  • Jingyi Yan,
  • Qian Zhang,
  • Hong Lin,
  • Lichao Zhu,
  • Qiangqiang Liu,
  • Changsheng Zhao

DOI
https://doi.org/10.1155/2020/4138696
Journal volume & issue
Vol. 2020

Abstract

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This study is aimed at exploring the relationship between serum ferritin and blood lipids and the influence of diabetes and different hs-CRP levels. A total of 8163 subjects were analyzed. Participators were classified according to serum ferritin, diabetes, and two hs-CRP levels. Blood lipids were determined using standardized methods and conditions. Except for HDL-C, there was a significant increase in blood lipids in the progressive ferritin group with normal hs-CRP levels (P0.05). After a sufficient adjustment, there was a positive correlation between serum TG and ferritin and a negative correlation between LDL-C and ferritin. Nonetheless, a negative correlation between LDL-C and ferritin is influenced by diabetes frailly. And, there was no change of relationship between lipids and ferritin in different hs-CRP levels. We found a real relationship between ferritin and lipids after sufficient adjustment for confounders.