Clinical, Cosmetic and Investigational Dermatology (Jul 2023)
A Case of Isotopic Response Presented with Eosinophilic Pustular Folliculitis
Abstract
Lulu Xv,* Bin Wang,* Qing Zhu, Guoqiang Zhang* The First Hospital of Hebei Medical University, Shijiazhuang, China*These authors contributed equally to this workCorrespondence: Guoqiang Zhang, No. 89, DongGang Road, Shijiazhuang, Hebei Province, People’s Republic of China, Tel +8618633888122, Email [email protected]: This is a 58-year-old woman who has had itching on her right back for 10 days; a month ago she developed blisters on her right back with no apparent cause and pain, and was diagnosed with “herpes zoster”. Erythema and blisters with itching reappeared 10 days ago on the right side of the back, where the original blisters had subsided. The histopathological manifestations of the lesions were: mild hyperkeratosis of the epidermis, pustules within the stratum corneum, irregular proliferation of the spinous layer, spongiosis, local destruction of the basal layer, infiltration of eosinophils, neutrophils, histiocytes and scattered plasma cells in the dermis and subcutis. According to the medical history, clinical manifestations and histopathology of the lesions, the diagnosis was Wolf’s isotopic response after herpes zoster.Keywords: Wolf’s isotopic response, herpes zoster, eosinophilic pustular folliculitis
