Nature Communications (Dec 2018)
Microtubule asters anchored by FSD1 control axoneme assembly and ciliogenesis
- Hai-Qing Tu,
- Xuan-He Qin,
- Zhi-Bin Liu,
- Zeng-Qing Song,
- Huai-Bin Hu,
- Yu-Cheng Zhang,
- Yan Chang,
- Min Wu,
- Yan Huang,
- Yun-Feng Bai,
- Guang Wang,
- Qiu-Ying Han,
- Ai-Ling Li,
- Tao Zhou,
- Feng Liu,
- Xue-Min Zhang,
- Hui-Yan Li
Affiliations
- Hai-Qing Tu
- State Key Laboratory of Proteomics, National Center of Biomedical Analysis
- Xuan-He Qin
- State Key Laboratory of Proteomics, National Center of Biomedical Analysis
- Zhi-Bin Liu
- University of Chinese Academy of Science
- Zeng-Qing Song
- State Key Laboratory of Proteomics, National Center of Biomedical Analysis
- Huai-Bin Hu
- State Key Laboratory of Proteomics, National Center of Biomedical Analysis
- Yu-Cheng Zhang
- State Key Laboratory of Proteomics, National Center of Biomedical Analysis
- Yan Chang
- State Key Laboratory of Proteomics, National Center of Biomedical Analysis
- Min Wu
- State Key Laboratory of Proteomics, National Center of Biomedical Analysis
- Yan Huang
- State Key Laboratory of Proteomics, National Center of Biomedical Analysis
- Yun-Feng Bai
- State Key Laboratory of Proteomics, National Center of Biomedical Analysis
- Guang Wang
- State Key Laboratory of Proteomics, National Center of Biomedical Analysis
- Qiu-Ying Han
- State Key Laboratory of Proteomics, National Center of Biomedical Analysis
- Ai-Ling Li
- State Key Laboratory of Proteomics, National Center of Biomedical Analysis
- Tao Zhou
- State Key Laboratory of Proteomics, National Center of Biomedical Analysis
- Feng Liu
- State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences
- Xue-Min Zhang
- State Key Laboratory of Proteomics, National Center of Biomedical Analysis
- Hui-Yan Li
- State Key Laboratory of Proteomics, National Center of Biomedical Analysis
- DOI
- https://doi.org/10.1038/s41467-018-07664-2
- Journal volume & issue
-
Vol. 9,
no. 1
pp. 1 – 17
Abstract
Microtubule asters originate from centrosomes but their role during interphase remains largely unknown. Here, the authors find that microtubule asters anchored by previously-uncharacterized FSD1 play a role in ciliogenesis by maintaining the dynamic localization of centriolar satellites.
