The effects of administration of nonselective inhibitor of NO-synthase under X-ray radiation

Abstract

Total activity of NO-synthetase and content of nitrates and nitrites in immu­no­competent cells of rat peripheral blood under the influence of fraction x-ray radiation and peroral administration of L-NAME were studied. It was shown that administration of L-NAME leads to inhibition of nitric oxide cytotoxic effect by reducing itproduction under the influence of low doses of x-ray radiation.

Keywords

• l-name
• no-synthase
• nitrates
• nitrites
• leukocytes
• x-ray radiation