Nasal Cytology: A Easy Diagnostic Tool in Precision Medicine for Inflammation in Epithelial Barrier Damage in the Nose. A Perspective Mini Review

Cristiano Caruso; Cristiano Caruso; Rossana Giancaspro; Giuseppe Guida; Alberto Macchi; Massimo Landi; Enrico Heffler; Enrico Heffler; Matteo Gelardi

doi:10.3389/falgy.2022.768408

Frontiers in Allergy (Apr 2022)

Nasal Cytology: A Easy Diagnostic Tool in Precision Medicine for Inflammation in Epithelial Barrier Damage in the Nose. A Perspective Mini Review

Cristiano Caruso,
Cristiano Caruso,
Rossana Giancaspro,
Giuseppe Guida,
Alberto Macchi,
Massimo Landi,
Enrico Heffler,
Enrico Heffler,
Matteo Gelardi

Affiliations

Cristiano Caruso: Unit of Internal Medicine and Gastroenterology, Department of Medical and Surgical Sciences, Agostino Gemelli University Polyclinic (IRCCS), Rome, Italy
Cristiano Caruso: Allergy Unit, Fondazione Policlinico A. Gemelli IRCCS, Rome, Italy
Rossana Giancaspro: Unit of Otolaryngology, Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy
Giuseppe Guida: Allergy and Pneumology Unit, A.O. S.Croce e Carle, Cuneo, Italy
Alberto Macchi: Italian Academy of Rhinology Asst Settelaghi-University of Insubriae, Varese, Italy
Massimo Landi: Paediatric National Healthcare System, Torino, Italy
Enrico Heffler: Personalized Medicine Center: Asthma and Allergology, Humanitas Research Hospital, Rozzano (MI), Italy
Enrico Heffler: Department of Biomedical Sciences, Humanitas University, Pieve Emanuele (MI), Italy
Matteo Gelardi: Unit of Otolaryngology, Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy

DOI: https://doi.org/10.3389/falgy.2022.768408
Journal volume & issue: Vol. 3

Abstract

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Nasal cytology is a diagnostic tool that can be used in precision rhinology medicine. Particularly in non-allergic rhinitis and chronic rhinosinusitis forms it can be useful to evaluate biomarkers of both surgical or biological therapy and especially in the follow-up it must be used to predict the prognostic index of recurrence of nasal polyposis. All inflammatory cytokines are also linked to the presence of cells such as eosinophils and mastcells and nasal cytology is a non-invasive and repeatable method to assess the situation in real life.

Published in Frontiers in Allergy

ISSN: 2673-6101 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Immunologic diseases. Allergy
Website: https://www.frontiersin.org/journals/allergy

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Abstract

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