B Lymphocytes, but Not Dendritic Cells, Efficiently HIV-1 <i>Trans</i> Infect Naive CD4 ⁺ T Cells: Implications for the Viral Reservoir

Abstract

The latent human immunodeficiency virus type 1 (HIV-1) reservoir in persons on antiretroviral therapy (ART) represents a major barrier to a cure. Although most studies have focused on the HIV-1 reservoir in the memory T cell subset, replication-competent HIV-1 has been isolated from T NnegN