EFFECT OF MODERATE DOSE OF INHALED BUDESONIDE ON HBA1C IN ASTHMATIC CHILDREN

Abstract

Objective: The objective of the study was to find out effect of inhaled corticosteroids on HbA1c. Methods: Asthma patients in the age group 5-15 years who were started on moderate doses of inhaled budesonide (400-800 microgram/day) for the first time were selected for the study. HbA1c level was measured before initiating inhaled corticosteroids (ICS) and after 6 months using venous blood samples. Results: The mean (SD) HbA1c levels before and after 6 months of starting inhaled corticosteroids was 4.75(0.16) and 5.25(0.29) respectively. The difference was statistically significant (p value <0.0001). After 6 months of inhaler use, HbA1c level of 5 patients (8.33%) reached at high risk level (5.7-6.4%). Conclusion: inhaled corticosteroids have a significant effect onHbA1c level after prolonged usage. We recommend monitoring HbA1c levels in children on long term inhaled corticosteroids.

Keywords

• Budesonide
• HbA1c
• Asthma
• Children