First report of anti-TIF1γ dermatomyositis in a patient with myelodysplastic syndrome

Abstract

Inflammatory myopathies as para-neoplastic phenomena were first described by Sterz in 1916. Recently, myositis specific autoantibodies were described in cancer-associated myositis. Anti-transcription intermediary factor 1 gamma (anti-TIF1γ) antibodies have been found in both young adults affected by juvenile dermatomyositis and in elderly patients with cancer-associated myositis. In this regard, we report herein the first case of anti-TIF1γ dermatomyositis secondary to a myelodysplastic syndrome.

Keywords

• Myelodisplastic syndrome
• Myositis specific autoantibodies
• Anti-TIF1γ
• Dermatomyositis.