Pulmonary Circulation (Jan 2024)

Plasma NEDD9 is increased following SARS‐CoV‐2 infection and associates with indices of pulmonary vascular dysfunction

  • George A. Alba,
  • Iris Y. Zhou,
  • Molly Mascia,
  • Michael Magaletta,
  • Jehan W. Alladina,
  • Francesca L. Giacona,
  • Leo C. Ginns,
  • Peter Caravan,
  • Bradley A. Maron,
  • Sydney B. Montesi

DOI
https://doi.org/10.1002/pul2.12356
Journal volume & issue
Vol. 14, no. 1
pp. n/a – n/a

Abstract

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Abstract Compared to healthy volunteers, participants with post‐acute sequelae of SARS‐CoV‐2 infection (PASC) demonstrated increased plasma levels of the prothrombotic protein NEDD9, which associated inversely with indices of pulmonary vascular function. This suggests persistent pulmonary vascular dysfunction may play a role in the pathobiology of PASC.

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