Functionalized Noble Metal Nanoparticles for the Treatment of Herpesvirus Infection

Martyna Janicka; Katarzyna Ranoszek-Soliwoda; Grzegorz Chodaczek; Małgorzata Antos-Bielska; Marek Brytan; Emilia Tomaszewska; Grzegorz Celichowski; Jarosław Grobelny; Joanna Cymerys; Małgorzata Krzyżowska; Marcin Chodkowski

doi:10.3390/microorganisms10112161

Microorganisms (Oct 2022)

Functionalized Noble Metal Nanoparticles for the Treatment of Herpesvirus Infection

Martyna Janicka,
Katarzyna Ranoszek-Soliwoda,
Grzegorz Chodaczek,
Małgorzata Antos-Bielska,
Marek Brytan,
Emilia Tomaszewska,
Grzegorz Celichowski,
Jarosław Grobelny,
Joanna Cymerys,
Małgorzata Krzyżowska,
Marcin Chodkowski

Affiliations

Martyna Janicka: Military Institute of Hygiene and Epidemiology, Kozielska 4, 01-163 Warsaw, Poland
Katarzyna Ranoszek-Soliwoda: Department of Materials Technology and Chemistry, Faculty of Chemistry, University of Lodz, Pomorska 163 St., 90-236 Lodz, Poland
Grzegorz Chodaczek: Bioimaging Laboratory, Łukasiewicz Research Network—PORT Polish Center for Technology Development, 54-066 Wroclaw, Poland
Małgorzata Antos-Bielska: Military Institute of Hygiene and Epidemiology, Kozielska 4, 01-163 Warsaw, Poland
Marek Brytan: Military Institute of Hygiene and Epidemiology, Kozielska 4, 01-163 Warsaw, Poland
Emilia Tomaszewska: Department of Materials Technology and Chemistry, Faculty of Chemistry, University of Lodz, Pomorska 163 St., 90-236 Lodz, Poland
Grzegorz Celichowski: Department of Materials Technology and Chemistry, Faculty of Chemistry, University of Lodz, Pomorska 163 St., 90-236 Lodz, Poland
Jarosław Grobelny: Department of Materials Technology and Chemistry, Faculty of Chemistry, University of Lodz, Pomorska 163 St., 90-236 Lodz, Poland
Joanna Cymerys: Division of Microbiology, Department of Preclinical Sciences, Institute of Veterinary Medicine, Warsaw University of Life Sciences, 02-786 Warsaw, Poland
Małgorzata Krzyżowska: Military Institute of Hygiene and Epidemiology, Kozielska 4, 01-163 Warsaw, Poland
Marcin Chodkowski: Military Institute of Hygiene and Epidemiology, Kozielska 4, 01-163 Warsaw, Poland

DOI: https://doi.org/10.3390/microorganisms10112161
Journal volume & issue: Vol. 10, no. 11
p. 2161

Abstract

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Neuroinfections caused by herpesviruses, mainly by HHV-1, represent a significant problem for modern medicine due to the small number of therapeutic substances available in the pharmaceutical sector. Furthermore, HHV-1 infection has been linked to neurodegenerative processes such as Alzheimer’s disease, which justifies the search for new effective therapies. The development of nanotechnology opens up new possibilities for the treatment of neuroinflammation. Gold and silver nanoparticles are gaining popularity, and the number of clinical trials involving metallic nanoparticles is constantly increasing. This paper reviews the research on gold and silver nanoparticles and their potential use in the treatment of herpesvirus neuroinfection.

Published in Microorganisms

ISSN: 2076-2607 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Biology (General)
Website: https://www.mdpi.com/journal/microorganisms

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