E2F4DN-BASED GENE THERAPY PREVENTS LONG-TERM POTENTIATION AND COGNITIVE LOSS AND IMPROVES NEURONAL SURVIVAL IN HOMOZYGOUS 5XFAD MICE.

• Cristina Sánchez-Puelles,
• Alberto Fraj,
• Vanesa Cano Daganzo,
• Alberto Garrido García,
• Gertrudis Perea,
• Jose María Frade

Affiliations

Cristina Sánchez-Puelles

Cajal Institute (CSIC), Molecular, Cellular And Developmental Neurobiology, Madrid, Spain; Tetraneuron S.L., I+d, Madrid, Spain

Alberto Fraj

Cajal Institute (CSIC), Molecular, Cellular And Developmental Neurobiology, Madrid, Spain

Vanesa Cano Daganzo

Cajal Institute (CSIC), Molecular, Cellular And Developmental Neurobiology, Madrid, Spain; Tetraneuron S.L., I+d, Madrid, Spain

Alberto Garrido García

Cajal Institute (CSIC), Molecular, Cellular And Developmental Neurobiology, Madrid, Spain; Tetraneuron S.L., I+d, Madrid, Spain

Gertrudis Perea

Cajal Institute (CSIC), Functional And Systems Neurobiology, Madrid, Spain

Jose María Frade

Cajal Institute (CSIC), Molecular, Cellular And Developmental Neurobiology, Madrid, Spain