Indian Journal of Ophthalmology (Jan 2013)
A unique case of phaeohyphomycosis subretinal abscess in a patient with arthropathy and lung pathology
- Bryan J Matthews,
- David Partridge,
- Richard M Sheard,
- Ian G Rennie,
- Hardeep Singh Mudhar
Affiliations
- Bryan J Matthews
- David Partridge
- Richard M Sheard
- Ian G Rennie
- Hardeep Singh Mudhar
- DOI
- https://doi.org/10.4103/0301-4738.124773
- Journal volume & issue
-
Vol. 61,
no. 12
pp. 763 – 765
Abstract
A 67-year-old former gold miner with rheumatoid arthritis, treated with steroids and methotrexate, presented to eye casualty with a painful right eye. Examination revealed an anterior uveitis and despite an initial response to topical steroids, the intraocular inflammation worsened with anterior and posterior uveitis development. Re-examination showed a white mass in the peripheral nasal retina initially suspected of being active Toxoplasmosis infection and anti-toxoplasmosis treatment commenced. After improvement and tapering of this treatment, the intraocular inflammation reoccurred. Cytopathological examination of a pars plana vitrectomy obtained vitreous sample that showed a non-diagnostic non-infectious chronic vitritis. The vitreoretinal surgeons elected to do a direct biopsy of the white subretinal mass in the peripheral nasal area. This revealed, quite unexpectedly, an abscess containing pigmented phaeohyphomycosis fungi. This case report documents the multidisciplinary approach that assisted in clinching a final diagnosis and the role of sub-retinal biopsy in this unprecedented scenario.
Keywords
- Amblyopia
- nasolacrimal duct obstruction
- probing
- Duane syndrome
- esotropia
- strabismus
- Bevacizumab
- mitochondrial function
- microvascular endothelial cells
- neurosensory retinal cells
- retinal pigment epithelial cells
- tissue culture
- Clinical donor tissue grading
- death to enucleation time
- death to preservation time
- eye bank specular microscopy
- optimizing donor tissue utilization
- DCR
- endodiathermy bipolar probe
- nasolacrimal duct obstruction
- recanalize
- Age-related macular degeneration
- carotenoids
- cross-sectional studies
- lutein
- Children
- GDx variable corneal compensation
- Indian
- normal
- retinal nerve fiber layer thickness
- Biological amniotic membrane
- 5-fluorouracil
- retina
- trabeculectomy
- Clinical features
- complications
- etiology
- retinal vasculitis
- Thailand
- Coloboma of the choroid
- coloboma optic disc
- indo cyanine green angiography
- vascular pattern
- Aphakia
- inadequate capsular support
- pediatric aphakia
- secondary intraocular lens implantation
- steel suture
- trans-scleral fixation
- vanadium steel
- Drug reaction
- drug-induced
- ranibizumab
- subacute cutaneous lupus erythematosus
- Prevalence
- rapid
- rapid assessment of refractive errors
- spectacles use
- uncorrected refractive errors
- visual impairment
- Bitemporal hemianopia
- Traumatic chiasmal syndrome
- visual field
- Phaeohyphomycosis
- pigmented fungi
- subretinal abscess
- subretinal biopsy