Communications Biology (Nov 2021)

The conserved single-cleavage mechanism of animal DROSHA enzymes

  • Thuy Linh Nguyen,
  • Trung Duc Nguyen,
  • Tuan Anh Nguyen

DOI
https://doi.org/10.1038/s42003-021-02860-1
Journal volume & issue
Vol. 4, no. 1
pp. 1 – 12

Abstract

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Recently, the human RNase III enzyme DROSHA had been shown to exhibit single cleavage activity. Nguyen et al. report that this molecular mechanism of DROSHA is conserved in worms and flies, suggesting a common feature of animal DROSHAs.