Nature Communications (Jan 2021)

TgAP2IX-5 is a key transcriptional regulator of the asexual cell cycle division in Toxoplasma gondii

  • Asma S. Khelifa,
  • Cecilia Guillen Sanchez,
  • Kevin M. Lesage,
  • Ludovic Huot,
  • Thomas Mouveaux,
  • Pierre Pericard,
  • Nicolas Barois,
  • Helene Touzet,
  • Guillemette Marot,
  • Emmanuel Roger,
  • Mathieu Gissot

DOI
https://doi.org/10.1038/s41467-020-20216-x
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 14

Abstract

Read online

The control of the proper timing of emergence of apicomplexan parasite daughter cells during replication is crucial for their proliferation. Here, Khelifa et al. identify a key transcriptional regulator in the model Apicomplexa Toxoplasma gondii, which regulates the expression of transcription factors necessary for completion of the budding cycle.