Nature Communications (Aug 2022)
Noninvasive imaging of the tumor immune microenvironment correlates with response to immunotherapy in gastric cancer
- Weicai Huang,
- Yuming Jiang,
- Wenjun Xiong,
- Zepang Sun,
- Chuanli Chen,
- Qingyu Yuan,
- Kangneng Zhou,
- Zhen Han,
- Hao Feng,
- Hao Chen,
- Xiaokun Liang,
- Shitong Yu,
- Yanfeng Hu,
- Jiang Yu,
- Yan Chen,
- Liying Zhao,
- Hao Liu,
- Zhiwei Zhou,
- Wei Wang,
- Wei Wang,
- Yikai Xu,
- Guoxin Li
Affiliations
- Weicai Huang
- Department of General Surgery, Nanfang Hospital, The First School of Clinical Medicine, Southern Medical University
- Yuming Jiang
- Department of General Surgery, Nanfang Hospital, The First School of Clinical Medicine, Southern Medical University
- Wenjun Xiong
- Department of Gastrointestinal Surgery, Guangdong Provincial Hospital of Chinese Medicine, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine
- Zepang Sun
- Department of General Surgery, Nanfang Hospital, The First School of Clinical Medicine, Southern Medical University
- Chuanli Chen
- Department of Medical Imaging Center, Nanfang Hospital, Southern Medical University
- Qingyu Yuan
- Department of Medical Imaging Center, Nanfang Hospital, Southern Medical University
- Kangneng Zhou
- School of Computer and Communication Engineering, University of Science and Technology Beijing
- Zhen Han
- Department of General Surgery, Nanfang Hospital, The First School of Clinical Medicine, Southern Medical University
- Hao Feng
- Department of General Surgery, Nanfang Hospital, The First School of Clinical Medicine, Southern Medical University
- Hao Chen
- Department of General Surgery, Nanfang Hospital, The First School of Clinical Medicine, Southern Medical University
- Xiaokun Liang
- Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences
- Shitong Yu
- Department of General Surgery, Nanfang Hospital, The First School of Clinical Medicine, Southern Medical University
- Yanfeng Hu
- Department of General Surgery, Nanfang Hospital, The First School of Clinical Medicine, Southern Medical University
- Jiang Yu
- Department of General Surgery, Nanfang Hospital, The First School of Clinical Medicine, Southern Medical University
- Yan Chen
- The Second Clinical Medical College, Guangzhou University of Chinese Medicine
- Liying Zhao
- Department of General Surgery, Nanfang Hospital, The First School of Clinical Medicine, Southern Medical University
- Hao Liu
- Department of General Surgery, Nanfang Hospital, The First School of Clinical Medicine, Southern Medical University
- Zhiwei Zhou
- Department of Gastric Surgery, Sun Yat-sen University Cancer Center
- Wei Wang
- Department of Gastrointestinal Surgery, Guangdong Provincial Hospital of Chinese Medicine, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine
- Wei Wang
- Department of Gastric Surgery, Sun Yat-sen University Cancer Center
- Yikai Xu
- Department of Medical Imaging Center, Nanfang Hospital, Southern Medical University
- Guoxin Li
- Department of General Surgery, Nanfang Hospital, The First School of Clinical Medicine, Southern Medical University
- DOI
- https://doi.org/10.1038/s41467-022-32816-w
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 14
Abstract
Tumour microenvironment has been linked with immunotherapy response in gastric cancer. Here, the authors use CT-based radiomics to predict neutrophils-to-lymphocyte ratio and response to immunotherapy.
