mBio (Jun 2021)
Caspase-Dependent Cleavage of DDX21 Suppresses Host Innate Immunity
- Wei Wu,
- Yang Qu,
- Shengqing Yu,
- Sa Wang,
- Yuncong Yin,
- Qinfang Liu,
- Chunchun Meng,
- Ying Liao,
- Zaib Ur Rehman,
- Lei Tan,
- Cuiping Song,
- Xusheng Qiu,
- Weiwei Liu,
- Chan Ding,
- Yingjie Sun
Affiliations
- Wei Wu
- Department of Avian Infectious Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Science, Shanghai, People’s Republic of China
- Yang Qu
- College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, People’s Republic of China
- Shengqing Yu
- ORCiD
- Department of Avian Infectious Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Science, Shanghai, People’s Republic of China
- Sa Wang
- College of Animal Sciences, Fujian Agriculture and Forestry University, Fuzhou, People’s Republic of China
- Yuncong Yin
- Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, People’s Republic of China
- Qinfang Liu
- ORCiD
- Department of Avian Infectious Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Science, Shanghai, People’s Republic of China
- Chunchun Meng
- Department of Avian Infectious Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Science, Shanghai, People’s Republic of China
- Ying Liao
- Department of Avian Infectious Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Science, Shanghai, People’s Republic of China
- Zaib Ur Rehman
- Department of Avian Infectious Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Science, Shanghai, People’s Republic of China
- Lei Tan
- Department of Avian Infectious Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Science, Shanghai, People’s Republic of China
- Cuiping Song
- Department of Avian Infectious Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Science, Shanghai, People’s Republic of China
- Xusheng Qiu
- Department of Avian Infectious Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Science, Shanghai, People’s Republic of China
- Weiwei Liu
- Department of Avian Infectious Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Science, Shanghai, People’s Republic of China
- Chan Ding
- Department of Avian Infectious Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Science, Shanghai, People’s Republic of China
- Yingjie Sun
- Department of Avian Infectious Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Science, Shanghai, People’s Republic of China
- DOI
- https://doi.org/10.1128/mBio.01005-21
- Journal volume & issue
-
Vol. 12,
no. 3
Abstract
Innate immunity serves as the first barrier against virus infection. DEAD (Glu-Asp-Ala-Glu) box RNA helicases, originally considered to be involved in RNA processing and RNA unwinding, have been shown to play an important role in antiviral innate immunity.
