Exploring the Diagnostic and Therapeutic Significance of Thyroid Hormones in Female Infertility: A Comprehensive Narrative Review

Abstract

Thyroid Hormones (TH) are essential for the healthy functioning of the female reproductive system because they regulate ovarian, uterine, and placental tissue metabolism and development. Therefore, hypo-and hyperthyroidism may result in infertility in women. Previous studies have been conducted on women with thyroid dysfunction, including prospective and retrospective studies, in-vitro and in-vivo tests for hypo-and hyperthyroidism using ovarian, uterine, and placental cell culture, and experimental animal models. In order to better understand the physiology of the reproductive system and to develop more effective therapy methods for reproductive dysfunctions that result from thyroid dysfunctions, these studies sought to shed light on the mechanisms by which TH affect reproduction. This comprehensive narrative review investigates the diagnostic and therapeutic implications of TH in female infertility. By scrutinising existing literature, the study aims to elucidate the intricate relationship between thyroid function and reproductive health in women. Such insights are crucial for enhancing diagnostic accuracy and formulating effective therapeutic interventions to address thyroid-related factors influencing female infertility.

Keywords

• female reproductive system
• hypothyroidism
• thyroid gland
• thyroid infertility