Zhongliu Fangzhi Yanjiu (Jul 2018)

Application Progress of 68Ga-PSMA PET/CT in Recurrent Prostate Cancer

  • YANG Liping,
  • LI Fuxing,
  • LI Wengui

DOI
https://doi.org/10.3971/j.issn.1000-8578.2018.17.1689
Journal volume & issue
Vol. 45, no. 7
pp. 505 – 509

Abstract

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The morbidity of prostate cancer (PCa) is high. Early diagnosis of recurrence after primary treatment is very important for the prognosis. Prostate specific membrane antigen (PSMA) is a transmembrane glycoprotein, with high expression in PCa. Small molecule inhibitors of the PSMA is labeled by 68Ga(68Ga-PSMA). 68Ga-PSMA is used as imaging agent for PET/CT imaging. 68Ga-PSMA PET/CT can display the distribution of prostate cancer in vivo. Many European and American countries have used 68Ga-PSMA PET/CT to find recurrent lesions in prostate cancer patients and achieved good results. This technology is still in its initial stage in China. This article reviews the research progress of 68Ga-PSMA PET/CT in prostate cancer recurrence, in order to improve the understanding of this new technology in China.

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