Platelet-rich plasma collection and preparation: a retrospective analysis of 256 cases

Lijuan YANG; Yan HU; Yajuan WU; Li ZHANG; Liping LIU; Tao PENG; Xinyu GAN

doi:10.13303/j.cjbt.issn.1004-549x.2023.10.021

Zhongguo shuxue zazhi (Oct 2023)

Platelet-rich plasma collection and preparation: a retrospective analysis of 256 cases

Lijuan YANG,
Yan HU,
Yajuan WU,
Li ZHANG,
Liping LIU,
Tao PENG,
Xinyu GAN

Affiliations

Lijuan YANG: Department of Blood Transfusion,the General Hospital of Western Theater Command, Chengdu 610036, China
Yan HU: Department of Blood Transfusion,the General Hospital of Western Theater Command, Chengdu 610036, China
Yajuan WU: Department of Blood Transfusion,the General Hospital of Western Theater Command, Chengdu 610036, China
Li ZHANG: Department of Blood Transfusion,the General Hospital of Western Theater Command, Chengdu 610036, China
Liping LIU: Department of Blood Transfusion,the General Hospital of Western Theater Command, Chengdu 610036, China
Tao PENG: Department of Blood Transfusion,the General Hospital of Western Theater Command, Chengdu 610036, China
Xinyu GAN: Department of Blood Transfusion,the General Hospital of Western Theater Command, Chengdu 610036, China

DOI: https://doi.org/10.13303/j.cjbt.issn.1004-549x.2023.10.021
Journal volume & issue: Vol. 36, no. 10
pp. 946 – 948

Abstract

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Objective To retrospectively analyze the safety and product quality of NGL XCF 3000 blood cell separator for collecting platelet-rich plasma (PRP) in 256 cases, so as to provide reference for safe collection and product quality control of PRP. Methods The data of 256 patients receiving PRP treatment in our hospital from June 2021 to June 2022 were statistically analyzed, and the differences in the collection time, circulating blood volume and the occurrence of adverse reactions to blood donation were analyzed when NGL XCF 3000 was used to collect autologous PRP among patients of different genders, ages and platelet counts. The differences in platelet content, red blood cell(RBC) contamination and white blood cell(WBC) residues in PRP products were analized. Results 1) There were no significant differences in collection time, circulating blood volume and collection volume among patients of different genders, ages and platelet counts (P<0.05). 2) The contents of WBC, RBC and platelet were not significantly different between male and female patients after collection (P<0.05); 3) The WBC contents increased with the increase of age, and the WBC residue in the elder group[ 56 to78 years old, (0.64±0.41) ×109/L] was significantly higher than that in the younger group[group 1,18 to 40 years old, (0.50±0.35)×109/L], with significant difference was Statistically significant (P<0.05). 4) The residues of WBCs and RBCs in in low platelet group [group 1, (100-150)×109/L] were higher than those in other platelet count groups, and the difference was Statistically significant (P<0.05), and the platelet count in this product was significantly lower than that in other platelet count groups (P<0.05). Conclusion The NGL XCF 3000 blood cell separator is safe and stable for PRP collection in patients with different genders, ages and platelet counts of (100-450)×109/L, and the PRP products collected can meet clinical therapeutic needs.

Published in Zhongguo shuxue zazhi

ISSN: 1004-549X (Print)
Publisher: Institute of Blood Transfusion of Chinese Academy of Medical Sciences
Country of publisher: China
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the blood and blood-forming organs
Website: https://www.cjbt.cn/homeNav?lang=en

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