cophesim: a comprehensive phenotype simulator for testing novel association methods [version 1; referees: 2 approved]

Abstract

Simulation is important in evaluating novel methods when input data is not easily obtainable or specific assumptions are needed. We present cophesim, a software to add the phenotype to generated genotype data prepared with a genetic simulator. The output of cophesim can be used as a direct input for different genome wide association study tools. cophesim is available from https://bitbucket.org/izhbannikov/cophesim.

Keywords

• Bioinformatics
• Genomics