Indian Journal of Animal Sciences (Nov 2022)

Expression spectrum of new circFBN1 in various tissues and follicles of Taihang chicken

  • TENG-HE MA,
  • MENG-XIAO LI,
  • BEI-BEI ZHANG,
  • XUE-NAN LI,
  • JIA-RONG WEI,
  • HONG-NA WANG,
  • BIN WANG,
  • YU-XIANG SHI

DOI
https://doi.org/10.56093/ijans.v92i11.127498
Journal volume & issue
Vol. 92, no. 11

Abstract

Read online

In this study, the new circFBN1 derived from the FBN1 gene was identified. The expression spectrum of circFBN1 in various tissues and follicles of Taihang chickens was verified and analyzed. The effects on proliferation of GCs were checked. The results revealed that circFBN1 is indeed present and was differentially expressed in tissues and follicles and significantly promoted cell proliferation. In conclusion, our results suggested that circFBN1 could affect chicken follicular development by regulating the proliferation of GCs. These results will enable us recognize the molecular mechanisms in animal reproductive regulation.

Keywords