Identification of a pro-angiogenic functional role for FSP1-positive fibroblast subtype in wound healing

Sarika Saraswati; Stephanie M. W. Marrow; Lester A. Watch; Pampee P. Young

doi:10.1038/s41467-019-10965-9

Nature Communications (Jul 2019)

Identification of a pro-angiogenic functional role for FSP1-positive fibroblast subtype in wound healing

Sarika Saraswati,
Stephanie M. W. Marrow,
Lester A. Watch,
Pampee P. Young

Affiliations

Sarika Saraswati: Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center
Stephanie M. W. Marrow: Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center
Lester A. Watch: Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center
Pampee P. Young: Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center

DOI: https://doi.org/10.1038/s41467-019-10965-9
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 16

Abstract

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Activated fibroblasts are key contributors to tissue repair after cardiac injury. Here, Saraswati et al. identify and characterize a subpopulation of FSP1-positive cardiac fibroblasts with proangiogenic properties in infarcted hearts.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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