Saudi Journal of Kidney Diseases and Transplantation (Jan 2010)

Simultaneous <i>Hodgkin&#x2032;s disease</i> and kaposi sarcoma in a renal transplant recipient

  • Yaich S,
  • Zagdane S,
  • Charfeddine K,
  • Hssairi D,
  • Hachicha J

Journal volume & issue
Vol. 21, no. 2
pp. 306 – 309

Abstract

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A 38-year-old women underwent first cadaver kidney transplantation. Her panel re-active antibody was 0%, and she had never previously been transfused nor pregnant. She received induction therapy with antithymoglobulin (ATG) as standard protocol and maintained on immuno-suppressive treatment of cyclosporine A, mycophenolate mofetil (MMF), and prednisone. Nine months after transplantation, she presented with anorexia, asthenia and weight loss. Cutaneous Ka-posi′s sarcoma and a Hodgkin disease were diagnosed. MMF was discontinued and cyclosporin A was switched to sirolimus. She also received a poly-chemotherapy associated with 4 courses of rituximab. Twelve months later, the patient had normal graft function and both malignancies were in complete remission.