Nature Communications (Feb 2021)
Divergent rhodium-catalyzed electrochemical vinylic C–H annulation of acrylamides with alkynes
Abstract
α-Pyridones and α-pyrones are ubiquitous structural motifs found in natural products and components of biologically active small molecules. Here, the authors report an oxidant-free Rh-catalyzed electrochemical divergent vinylic C–H annulation of acrylamides with alkynes to α-pyridones and cyclic imidates.