Nature Communications (Mar 2021)

Unc13A and Unc13B contribute to the decoding of distinct sensory information in Drosophila

  • Atefeh Pooryasin,
  • Marta Maglione,
  • Marco Schubert,
  • Tanja Matkovic-Rachid,
  • Sayed-mohammad Hasheminasab,
  • Ulrike Pech,
  • André Fiala,
  • Thorsten Mielke,
  • Stephan J. Sigrist

DOI
https://doi.org/10.1038/s41467-021-22180-6
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 14

Abstract

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The physical distance between synaptic Ca2+ channels and sensors modulates short-term plasticity (STP). Here, the authors show that synaptic release factors Unc13A and Unc13B distinctly couple with Ca2+ channels and contribute to the neural decoding of distinct sensory information in Drosophila.