Efficient Synthesis and Antimicrobial Activity of 2-Pyridyl-4-thiazolidinones from 2-Chloro Nicotinaldehydes

Abstract

Several new 2-pyridyl-4-thiazolidinones are synthesized in an efficient manner evading using any catalyst or base. Simple workup procedure, good yields, and mild reaction conditions are the salient features of this method. All the synthesized compounds are screened for antimicrobial activity against several organisms.

Keywords

• 2-chloro nicotinaldehyde
• catalyst-free reaction
• thiazolidinone
• antimicrobial activity