Química Nova (Aug 2004)

Constituintes químicos de Melaleuca alternifolia (Myrtaceae) Chemical constituents from Melaleuca alternifolia (Myrtaceae)

  • Tatiana R. Vieira,
  • Luiz C. A. Barbosa,
  • Célia R. A. Maltha,
  • Vanderlúcia F. Paula,
  • Evandro A. Nascimento

DOI
https://doi.org/10.1590/S0100-40422004000400004
Journal volume & issue
Vol. 27, no. 4
pp. 536 – 539

Abstract

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The first chemical study of non-volatile constituents from the bark and stem of Melaleuca alternifolia (Myrtaceae) led to the isolation and identification of 3,3'-O-dimethylellagic acid (1) and five pentacyclic triterpenes: 2alpha,3beta,23-trihydroxyolean-12-en-28-oic acid (arjunolic acid, 2), 3beta-hydroxylup-20(29)-en-27,28-dioic acid (melaleucic acid, 3), betulinic acid (4), betuline (5), 3beta-O-acetylurs-12-en-28-oic acid (6), a mixture of fatty acids and esters, and several hydrocarbons. For 2alpha,3beta,23-trihydroxyolean-12-en-28-oic acid (2) and 3beta-O-acetylurs-12-en-28-oic acid (6) a first detailed assignment of ¹H NMR is presented.

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