Maternal and neonatal outcomes of pregnant women with SARS-CoV-2 infection in our tertiary hospital

Abstract

Objective: To evaluate clinical features, laboratory test results, and maternal and neonatal outcomes of pregnant patients with the Coronavirus disease (COVID-19). Methods: We reviewed clinical data from pregnant women with a laboratory-confirmed SARS-CoV-2, who were admitted to our university hospital in Türkiye. Demographic and clinical characteristics, laboratory test results, and maternal and neonatal outcomes were collected. Results: A total of 46 pregnant women were included in this study. The mean maternal age was 28 (min. 21 – max. 39) years and gestational age was 31 (min. 26 – max. 41) weeks. Two (4.37%) pregnant women were vaccinated with 1 dose of BioNTech® vaccine, and all other patients were unvaccinated. Shortness of breath was the most common symptom present in 15 cases (32.6%). Twenty-seven (58.69%) pregnant women gave birth in the preterm period, and 19 (41.30%) in the term period. Six (13.04%) pregnant women were followed up in the Anesthesia Intensive Care Unit. Two women with critical COVID-19 died in the postpartum period. Conclusion: COVID-19 infection has negative consequences in terms of maternal and neonatal outcomes. The most common causes of adverse neonatal outcomes are iatrogenic or spontaneous preterm births, while the most common causes of adverse maternal outcomes are prolonged hospitalization time, increased likelihood of intensive care hospitalization, and maternal deaths. The most effective way to prevent this situation is to get vaccinated regardless of trimester.