EFFECT OF DOPED CERIUM OXIDE NANOPARTICLES ON THE HAEMATOLOGY OF RATS

Abstract

Cerium is a rare earth lanthanide and a strong oxidizing agent. It has got a wide range of application from engendering to medicinal field. Potential amount of harm also reported about this particle. Recent days it is used as diesel fuel additive and doped with yttrium and zirconium nanoparticles to increase its oxygen caring capacity. Hence a study designed to study about the impact on the environment taking rat as model. A total no of 36 rats were taken and divided into six groups contains six animals each. Control animals served with normal saline and treatment animals administered intratracheally with 4 and 8 mg/kg body weight of this particles. The higher dose group showed increased levels of hemoglobin but other parameters had no significant difference among any group. The increased level of hemoglobin was suggestive of blood vascular changes.

Keywords

• doped cerium
• diesel fuel
• intratracheal