mBio (Feb 2021)
Molecular Signatures of Inflammatory Profile and B-Cell Function in Patients with Severe Fever with Thrombocytopenia Syndrome
- Angela Park,
- Su-Jin Park,
- Kyle L. Jung,
- Se Mi Kim,
- Eun-Ha Kim,
- Young-Il Kim,
- Suan-Sin Foo,
- Sunghyun Kim,
- Seong-Gyu Kim,
- Kwang-Min Yu,
- Younho Choi,
- Ji Yeun Kim,
- Yun Hee Baek,
- Min-Suk Song,
- Seung Ryul Kim,
- Seok-Yong Kim,
- Hye Won Jeong,
- Sung-Han Kim,
- Jae U. Jung,
- Young Ki Choi
Affiliations
- Angela Park
- Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
- Su-Jin Park
- College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea
- Kyle L. Jung
- Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
- Se Mi Kim
- College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea
- Eun-Ha Kim
- College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea
- Young-Il Kim
- ORCiD
- College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea
- Suan-Sin Foo
- Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
- Sunghyun Kim
- Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
- Seong-Gyu Kim
- College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea
- Kwang-Min Yu
- College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea
- Younho Choi
- Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
- Ji Yeun Kim
- Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
- Yun Hee Baek
- College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea
- Min-Suk Song
- ORCiD
- College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea
- Seung Ryul Kim
- College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea
- Seok-Yong Kim
- College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea
- Hye Won Jeong
- College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea
- Sung-Han Kim
- Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
- Jae U. Jung
- ORCiD
- Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
- Young Ki Choi
- ORCiD
- College of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Republic of Korea
- DOI
- https://doi.org/10.1128/mBio.02583-20
- Journal volume & issue
-
Vol. 12,
no. 1
Abstract
SFTSV is an emerging virus discovered in China in 2009; it has since spread to other countries in East Asia. Although the fatality rates of SFTSV infection range from 5.3% to as high as 27%, the mechanisms underlying clinical manifestations are largely unknown.
