Ciencia UNEMI (Aug 2017)

Caracterización clínica e histopatológica de la infección por Papiloma Virus humano de muestras de cérvix. Hospital Teodoro Maldonado Carbo “IESS”

  • Bedoya, César,
  • Sánchez-Giler, Sunny,
  • Zambrano, Dolores,
  • Herrera, Alan,
  • Silva, Alba,
  • Kuon-Yeng, Cristina,
  • Feliz, Emilio,
  • Vera, Carlos,
  • Mateo, Belén,
  • Sotomayor, Doménica,
  • Murillo, Juan- Pablo,
  • Marriot, Denisse,
  • Cevallos, Kerly,
  • Espinosa, Maylen,
  • España, Karol

Journal volume & issue
Vol. 10, no. 23
pp. 105 – 111

Abstract

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Human Papilloma Virus (HPV) has a predilection for poly-stratified tissues, with persistence in the basal layers, hence mainly is the etiological agent of cervical cancer. Cervical cancer is the second most common cancer in women worldwide. HPV is unique oncogenic infectious agent that causes it. The objective of the study was to determine the prevalence of the virus in women, using DNA detection techniques through PCR, in real-time, from the cervical biopsy. In addition, the related histopathological and clinical characteristics were established. The prevalence was 30.67%, the most frequently infected histopathology presentation was cervical and in situ cancer. The more dysplastic the histopathology of the cervix, the more frequent the presentation of the virus. An association between exposure to infection and the presence of whitish vaginal discharge and dyspareunia was demonstrated.

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