New pathways for the synthesis of indolyl-containing quinazoline trifluoroacetohydrazides

Abstract

The reactions of indole-3-carbaldehyde arylhydrazones with quinazoline in TFA proceed at the 7' position of the aryl part of the hydrazone molecule to form σ-adducts of quinazoline trifluoroacetohydrazides.

Keywords

• arylhydrazones
• indole-3-carboxaldehydes
• с,с-coupling
• trifluoroacetyl quinazoline hydrazides