PLoS ONE (Jan 2014)

Predicting perioperative venous thromboembolism in Japanese gynecological patients.

  • Masae Ikeda,
  • Hidetoshi Kan-no,
  • Masaru Hayashi,
  • Hitomi Tsukada,
  • Masako Shida,
  • Takeshi Hirasawa,
  • Toshinari Muramatsu,
  • Yoichi Ogushi,
  • Mikio Mikami

DOI
https://doi.org/10.1371/journal.pone.0089206
Journal volume & issue
Vol. 9, no. 2
p. e89206

Abstract

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ObjectiveTo develop a convenient screening method that can predict perioperative venous thromboembolism (VTE) and identify patients at risk of fatal perioperative pulmonary embolism (PE).MethodsPatients hospitalized for gynecological abdominal surgery (n = 183) underwent hematology tests and multidetector computed tomography (MDCT) to detect VTE. All statistical analyses were carried out using the SPSS software program (PASWV19.0J).ResultsThe following risk factors for VTE were identified by univariate analysis: plasmin-alpha2-plasmin inhibitor complex (PIC), thrombin-antithrombin III complex (TAT), and prolonged immobility (all pConclusionsWe propose new screening criteria for VTE risk that are based on PIC, transverse tumor diameter, and age. Our findings suggest the usefulness of these criteria for predicting the risk of perioperative VTE and for identifying patients with a high risk of fatal perioperative PE.