Zinc-doped Prussian blue enhances photothermal clearance of Staphylococcus aureus and promotes tissue repair in infected wounds

Jun Li; Xiangmei Liu; Lei Tan; Zhenduo Cui; Xianjin Yang; Yanqin Liang; Zhaoyang Li; Shengli Zhu; Yufeng Zheng; Kelvin Wai Kwok Yeung; Xianbao Wang; Shuilin Wu

doi:10.1038/s41467-019-12429-6

Nature Communications (Oct 2019)

Zinc-doped Prussian blue enhances photothermal clearance of Staphylococcus aureus and promotes tissue repair in infected wounds

Jun Li,
Xiangmei Liu,
Lei Tan,
Zhenduo Cui,
Xianjin Yang,
Yanqin Liang,
Zhaoyang Li,
Shengli Zhu,
Yufeng Zheng,
Kelvin Wai Kwok Yeung,
Xianbao Wang,
Shuilin Wu

Affiliations

Jun Li: School of Materials Science and Engineering, The Key Laboratory of Advanced Ceramics and Machining Technology by the Ministry of Education of China, Tianjin University
Xiangmei Liu: Ministry-of-Education Key Laboratory for the Green Preparation and Application of Functional Materials, Hubei Key Laboratory of Polymer Materials, School of Materials Science and Engineering, Hubei University
Lei Tan: Ministry-of-Education Key Laboratory for the Green Preparation and Application of Functional Materials, Hubei Key Laboratory of Polymer Materials, School of Materials Science and Engineering, Hubei University
Zhenduo Cui: School of Materials Science and Engineering, The Key Laboratory of Advanced Ceramics and Machining Technology by the Ministry of Education of China, Tianjin University
Xianjin Yang: School of Materials Science and Engineering, The Key Laboratory of Advanced Ceramics and Machining Technology by the Ministry of Education of China, Tianjin University
Yanqin Liang: School of Materials Science and Engineering, The Key Laboratory of Advanced Ceramics and Machining Technology by the Ministry of Education of China, Tianjin University
Zhaoyang Li: School of Materials Science and Engineering, The Key Laboratory of Advanced Ceramics and Machining Technology by the Ministry of Education of China, Tianjin University
Shengli Zhu: School of Materials Science and Engineering, The Key Laboratory of Advanced Ceramics and Machining Technology by the Ministry of Education of China, Tianjin University
Yufeng Zheng: State Key Laboratory for Turbulence and Complex System and Department of Materials Science and Engineering, College of Engineering, Peking University
Kelvin Wai Kwok Yeung: Department of Orthopaedics and Traumatology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam
Xianbao Wang: Ministry-of-Education Key Laboratory for the Green Preparation and Application of Functional Materials, Hubei Key Laboratory of Polymer Materials, School of Materials Science and Engineering, Hubei University
Shuilin Wu: School of Materials Science and Engineering, The Key Laboratory of Advanced Ceramics and Machining Technology by the Ministry of Education of China, Tianjin University

DOI: https://doi.org/10.1038/s41467-019-12429-6
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 15

Abstract

Read online

Here, the authors apply transition metal doping in combination with phototermal therapy to treat Staphylococcus aureus-infected wounds, and show that release of ions by local heat enhances bacteria clearance and promotes tissue repair in a rat model of MRSA-infected wounds

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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