Nature Communications (Nov 2020)
Organized cannabinoid receptor distribution in neurons revealed by super-resolution fluorescence imaging
- Hui Li,
- Jie Yang,
- Cuiping Tian,
- Min Diao,
- Quan Wang,
- Simeng Zhao,
- Shanshan Li,
- Fangzhi Tan,
- Tian Hua,
- Ya Qin,
- Chao-Po Lin,
- Dylan Deska-Gauthier,
- Garth J. Thompson,
- Ying Zhang,
- Wenqing Shui,
- Zhi-Jie Liu,
- Tong Wang,
- Guisheng Zhong
Affiliations
- Hui Li
- iHuman Institute, ShanghaiTech University
- Jie Yang
- iHuman Institute, ShanghaiTech University
- Cuiping Tian
- iHuman Institute, ShanghaiTech University
- Min Diao
- iHuman Institute, ShanghaiTech University
- Quan Wang
- iHuman Institute, ShanghaiTech University
- Simeng Zhao
- iHuman Institute, ShanghaiTech University
- Shanshan Li
- iHuman Institute, ShanghaiTech University
- Fangzhi Tan
- iHuman Institute, ShanghaiTech University
- Tian Hua
- iHuman Institute, ShanghaiTech University
- Ya Qin
- School of Life Science and Technology, ShanghaiTech University
- Chao-Po Lin
- School of Life Science and Technology, ShanghaiTech University
- Dylan Deska-Gauthier
- Department of Medical Neuroscience, Dalhousie University
- Garth J. Thompson
- iHuman Institute, ShanghaiTech University
- Ying Zhang
- Department of Medical Neuroscience, Dalhousie University
- Wenqing Shui
- iHuman Institute, ShanghaiTech University
- Zhi-Jie Liu
- iHuman Institute, ShanghaiTech University
- Tong Wang
- School of Life Science and Technology, ShanghaiTech University
- Guisheng Zhong
- iHuman Institute, ShanghaiTech University
- DOI
- https://doi.org/10.1038/s41467-020-19510-5
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 12
Abstract
Despite the importance of G-protein-coupled receptors in many cellular functions, their intracellular organisation is largely unknown. The authors identified periodically repeating clusters of cannabinoid receptor 1 hotspots within neuronal axons that are dynamically regulated by CB1 agonists.
