Alexandria Engineering Journal (Jun 2020)

Growth of tumor due to Arsenic and its mitigation by black tea in Swiss albino mice

  • H.M. Srivastava,
  • Urmimala Dey,
  • Archismaan Ghosh,
  • Jai Prakash Tripathi,
  • Syed Abbas,
  • A. Taraphder,
  • Madhumita Roy

Journal volume & issue
Vol. 59, no. 3
pp. 1345 – 1357

Abstract

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Inorganic arsenic causes carcinogenesis in a large part of the world. Its potential is elicited by the generation of ROS, which leads to damages to DNA, lipid and protein. Black tea, an antioxidant, can mitigate such deleterious effects by quenching ROS. We study Arsenic-toxicity and its amelioration by black tea in a colony of albino mice: a homology exists between the protein coding regions of mice and human. We observe that black tea has salutary effects on tumor-growth: it arrests damaged cell growth and produces early saturation of the damage. The experimental data obtained by us are modelled with dynamical equations. This is followed by a search for steady states and their stability analysis.

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