Glibenclamide therapy: pros and cons

Abstract

The safety of antidiabetic medications has received much attention in the resent past. Although concerns on the safety of glibenclamide therapy iscontroversial, some studies showed an increased risk of cardiovascular morbidity (f.e. myocardial infarction) and risk of mortality in subjects usingglibenclamide, but not other SU (gliclazide or glimepiride)

Keywords

• diabetes mellitus type 2
• glibenclamide
• hypoglysemia
• mortality