Journal of Pharmacy and Bioallied Sciences (Apr 2024)

Green Synthesis of Mimosa pudica-Mediated Strontium Nanoparticles and its Anti-Inflammatory Activity

  • Harshini Sakthi,
  • Shanmugam Rajeshkumar,
  • Govindharaj Sulochana

DOI
https://doi.org/10.4103/jpbs.jpbs_586_23
Journal volume & issue
Vol. 16, no. 6
pp. 1335 – 1339

Abstract

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BackgroundConsiderable focus has been directed toward green synthesis as a dependable, sustainable, and environmentally friendly approach for synthesizing various nanomaterials. Mimosa pudica, a quickly grown pantropical weed, has been used widely for its anti-inflammatory and antimicrobial activity in traditional medicine. The development of strontium-based nanoparticles and nanoparticles linked with strontium has garnered attention in recent years due to their established utility in diverse domains such as effective drug distribution, bioimaging, cancer treatment, and advancements in bone engineering. Aims and ObjectivesTo examine the green synthesise of strontium nanoparticles using Mimosa pudica and its anti-inflammatory activity. Material and MethodsMimosa pudica-mediated strontium nanoparticles’ anti-inflammatory activity was tested using bovine serum albumin denaturation assay, egg albumin denaturation assay, and membrane stabilization assay with diclofenac sodium as the standard. Result: In all three assays, increasing concentration of Mimosa pudica-mediated strontium nanoparticles exhibited an increasing anti-inflammatory effect, which was similar to the standard diclofenac sodium. ConclusionConsequently, this holds promise as a new potential anti-inflammatory agent in forthcoming applications.

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