Mechanism and biomass association of glucuronoyl esterase: an α/β hydrolase with potential in biomass conversion

Zhiyou Zong; Scott Mazurkewich; Caroline S. Pereira; Haohao Fu; Wensheng Cai; Xueguang Shao; Munir S. Skaf; Johan Larsbrink; Leila Lo Leggio

doi:10.1038/s41467-022-28938-w

Nature Communications (Mar 2022)

Mechanism and biomass association of glucuronoyl esterase: an α/β hydrolase with potential in biomass conversion

Zhiyou Zong,
Scott Mazurkewich,
Caroline S. Pereira,
Haohao Fu,
Wensheng Cai,
Xueguang Shao,
Munir S. Skaf,
Johan Larsbrink,
Leila Lo Leggio

Affiliations

Zhiyou Zong: Department of Chemistry, University of Copenhagen
Scott Mazurkewich: Wallenberg Wood Science Center, Division of Industrial Biotechnology, Department of Biology and Biological Engineering, Chalmers University of Technology
Caroline S. Pereira: Institute of Chemistry and Center for Computing in Engineering and Sciences, University of Campinas – Unicamp
Haohao Fu: College of Chemistry, Research Center for Analytical Sciences, Tianjin Key Laboratory of Biosensing and Molecular Recognition, State Key Laboratory of Medicinal Chemical Biology, Nankai University
Wensheng Cai: College of Chemistry, Research Center for Analytical Sciences, Tianjin Key Laboratory of Biosensing and Molecular Recognition, State Key Laboratory of Medicinal Chemical Biology, Nankai University
Xueguang Shao: College of Chemistry, Research Center for Analytical Sciences, Tianjin Key Laboratory of Biosensing and Molecular Recognition, State Key Laboratory of Medicinal Chemical Biology, Nankai University
Munir S. Skaf: Institute of Chemistry and Center for Computing in Engineering and Sciences, University of Campinas – Unicamp
Johan Larsbrink: Wallenberg Wood Science Center, Division of Industrial Biotechnology, Department of Biology and Biological Engineering, Chalmers University of Technology
Leila Lo Leggio: Department of Chemistry, University of Copenhagen

DOI: https://doi.org/10.1038/s41467-022-28938-w
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 10

Abstract

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Zong and coworkers combine computational and experimental methods to decipher in detail the mechanism of action of glucuronoyl esterases, enzymes with significant biotechnological potential for decoupling lignin from polysaccharides in biomass.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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