The effect of recombinant interferon alpha-2b on the relative content of CD56^bright NK cells in the peripheral blood of pregnant women with chronic urogenital infections

Abstract

Physiological immunodeficiency during pregnancy contributes to activation of chronic urogenital pathology which often causes intrauterine infections. Recombinant interferon-alpha based rectal suppositories VIFERON® are often used in Russia for treatment of pregnant women with urogenital pathology. The treatment results in a marked decrease in the number of pregnancy complications and perinatal pathology accompanied by a decrease in peripheral blood CD56bright natural killer cells.

Keywords

• беременность
• урогенитальные инфекции
• внутриутробные инфекции
• рекомбинантный интерферон альфа-2b
• cd56^bright-популяция натуральных киллеров
• pregnancy
• urogenital pathology
• intrauterine infections
• recombinant interferon-alpha
• cd56^bright natural killer cells