Theranostic barcoded nanoparticles for personalized cancer medicine

Zvi Yaari; Dana da Silva; Assaf Zinger; Evgeniya Goldman; Ashima Kajal; Rafi Tshuva; Efrat Barak; Nitsan Dahan; Dov Hershkovitz; Mor Goldfeder; Janna Shainsky Roitman; Avi Schroeder

doi:10.1038/ncomms13325

Nature Communications (Nov 2016)

Theranostic barcoded nanoparticles for personalized cancer medicine

Zvi Yaari,
Dana da Silva,
Assaf Zinger,
Evgeniya Goldman,
Ashima Kajal,
Rafi Tshuva,
Efrat Barak,
Nitsan Dahan,
Dov Hershkovitz,
Mor Goldfeder,
Janna Shainsky Roitman,
Avi Schroeder

Affiliations

Zvi Yaari: Department of Chemical Engineering, Laboratory for Targeted Drug Delivery and Personalized Medicine Technologies, Technion—Israel Institute of Technology
Dana da Silva: Department of Chemical Engineering, Laboratory for Targeted Drug Delivery and Personalized Medicine Technologies, Technion—Israel Institute of Technology
Assaf Zinger: Department of Chemical Engineering, Laboratory for Targeted Drug Delivery and Personalized Medicine Technologies, Technion—Israel Institute of Technology
Evgeniya Goldman: Department of Chemical Engineering, Laboratory for Targeted Drug Delivery and Personalized Medicine Technologies, Technion—Israel Institute of Technology
Ashima Kajal: Department of Chemical Engineering, Laboratory for Targeted Drug Delivery and Personalized Medicine Technologies, Technion—Israel Institute of Technology
Rafi Tshuva: Department of Chemical Engineering, Laboratory for Targeted Drug Delivery and Personalized Medicine Technologies, Technion—Israel Institute of Technology
Efrat Barak: Infrastructure Unit, Life Science and Engineering Center, Technion—Israel Institute of Technology
Nitsan Dahan: Infrastructure Unit, Life Science and Engineering Center, Technion—Israel Institute of Technology
Dov Hershkovitz: Clinical Pathology Unit, Rambam Medical Center
Mor Goldfeder: Department of Chemical Engineering, Laboratory for Targeted Drug Delivery and Personalized Medicine Technologies, Technion—Israel Institute of Technology
Janna Shainsky Roitman: Department of Chemical Engineering, Laboratory for Targeted Drug Delivery and Personalized Medicine Technologies, Technion—Israel Institute of Technology
Avi Schroeder: Department of Chemical Engineering, Laboratory for Targeted Drug Delivery and Personalized Medicine Technologies, Technion—Israel Institute of Technology

DOI: https://doi.org/10.1038/ncomms13325
Journal volume & issue: Vol. 7, no. 1
pp. 1 – 10

Abstract

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Determining the most effective treatment for each cancer patient is a key challenge in cancer therapy. In this article, the authors show, in a mouse model of breast cancer, that DNA barcoded nanoparticles can be used for pre-screening the efficacy of anticancer drugs.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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