Nature Communications (Dec 2020)

Establishing a mass spectrometry-based system for rapid detection of SARS-CoV-2 in large clinical sample cohorts

  • Karina Helena Morais Cardozo,
  • Adriana Lebkuchen,
  • Guilherme Gonçalves Okai,
  • Rodrigo Andrade Schuch,
  • Luciana Godoy Viana,
  • Aline Nogueira Olive,
  • Carolina dos Santos Lazari,
  • Ana Maria Fraga,
  • Celso Francisco Hernandes Granato,
  • Maria Carolina Tostes Pintão,
  • Valdemir Melechco Carvalho

DOI
https://doi.org/10.1038/s41467-020-19925-0
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 13

Abstract

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Large population testing is a key step to controlling the COVID-19 pandemic. Here, the authors develop a targeted mass spectrometry system for peptide-based SARS-CoV-2 detection, allowing analysis of over 500 swab samples per day and enabling virus detection even after prolonged sample storage at room temperature.