Sortase-Mediated Site-Specific Modification of Interleukin‑2 for the Generation of a Tumor-Targeting Acetazolamide–Cytokine Conjugate

• Baptiste Gouyou,
• Jacopo Millul,
• Alessandra Villa,
• Samuele Cazzamalli,
• Dario Neri,
• Mattia Matasci

Affiliations

Baptiste Gouyou

Philochem AG, Otelfingen, Switzerland

Jacopo Millul

Philochem AG, Otelfingen, Switzerland

Alessandra Villa

Philochem AG, Otelfingen, Switzerland

Samuele Cazzamalli

Philochem AG, Otelfingen, Switzerland

Dario Neri

Department of Chemistry and Applied Biosciences, Swiss Federal Institute of Technology, Zurich, Switzerland

Mattia Matasci

Philochem AG, Otelfingen, Switzerland