Programmable polymorphism of a virus-like particle

Artur P. Biela; Antonina Naskalska; Farzad Fatehi; Reidun Twarock; Jonathan G. Heddle

doi:10.1038/s43246-022-00229-3

Communications Materials (Feb 2022)

Programmable polymorphism of a virus-like particle

Artur P. Biela,
Antonina Naskalska,
Farzad Fatehi,
Reidun Twarock,
Jonathan G. Heddle

Affiliations

Artur P. Biela: Malopolska Centre of Biotechnology, Jagiellonian University
Antonina Naskalska: Malopolska Centre of Biotechnology, Jagiellonian University
Farzad Fatehi: Departments of Mathematics, University of York
Reidun Twarock: Departments of Mathematics, University of York
Jonathan G. Heddle: Malopolska Centre of Biotechnology, Jagiellonian University

DOI: https://doi.org/10.1038/s43246-022-00229-3
Journal volume & issue: Vol. 3, no. 1
pp. 1 – 9

Abstract

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Virus-like particles are promising for drug delivery systems and vaccine development, but controlling their size and morphology is challenging. Here, amino acid sequences are inserted into MS2 bacteriophage virus-like particles, with their size and shape being controlled by varying the insert used.

Published in Communications Materials

ISSN: 2662-4443 (Online)
Publisher: Nature Portfolio
Country of publisher: United States
LCC subjects: Technology: Electrical engineering. Electronics. Nuclear engineering: Materials of engineering and construction. Mechanics of materials
Website: https://www.nature.com/commsmat/

About the journal