Generation of induced pluripotent stem cells from a patient with X-linked juvenile retinoschisis

Chi-Hsien Peng; Kang-Chieh Huang; Huai-En Lu; Shih-Han Syu; Aliaksandr A. Yarmishyn; Jyh-Feng Lu; Waradee Buddhakosai; Tai-Chi Lin; Chih-Chien Hsu; De-Kuang Hwang; Chia-Ning Shen; Shih-Jen Chen; Shih-Hwa Chiou

Stem Cell Research (May 2018)

Generation of induced pluripotent stem cells from a patient with X-linked juvenile retinoschisis

Chi-Hsien Peng,
Kang-Chieh Huang,
Huai-En Lu,
Shih-Han Syu,
Aliaksandr A. Yarmishyn,
Jyh-Feng Lu,
Waradee Buddhakosai,
Tai-Chi Lin,
Chih-Chien Hsu,
De-Kuang Hwang,
Chia-Ning Shen,
Shih-Jen Chen,
Shih-Hwa Chiou

Affiliations

Chi-Hsien Peng: Department of Ophthalmology, Shin Kong Wu Ho-Su Memorial Hospital, Fu-Jen Catholic University, Taipei, Taiwan
Kang-Chieh Huang: Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan
Huai-En Lu: Bioresource Collection and Research Center, Food Industry Research and Development Institute, Hsinchu, Taiwan
Shih-Han Syu: Bioresource Collection and Research Center, Food Industry Research and Development Institute, Hsinchu, Taiwan
Aliaksandr A. Yarmishyn: Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan
Jyh-Feng Lu: School of Medicine, Fu Jen Catholic University, Taipei, Taiwan
Waradee Buddhakosai: Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan
Tai-Chi Lin: Institute of Clinical Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan; Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan
Chih-Chien Hsu: Institute of Clinical Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan; Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan
De-Kuang Hwang: Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan; School of Medicine, National Yang-Ming University, Taipei, Taiwan
Chia-Ning Shen: Genomic Research Center, Academia Sinica, Taipei, Taiwan
Shih-Jen Chen: Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan; School of Medicine, National Yang-Ming University, Taipei, Taiwan
Shih-Hwa Chiou: Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan; Genomic Research Center, Academia Sinica, Taipei, Taiwan; Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan; Corresponding author at: Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan.

Journal volume & issue: Vol. 29
pp. 152 – 156

Abstract

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X-linked juvenile retinoschisis (XLRS) is a hereditary retinal dystrophy manifested as splitting of anatomical layers of retina. In this report, we generated a patient-specific induced pluripotent stem cell (iPSC) line, TVGH-iPSC-013-05, from the peripheral blood mononuclear cells of a male patient with XLRS by using the Sendai-virus delivery system. We believe that XLRS patient-specific iPSCs provide a powerful in vitro model for evaluating the pathological phenotypes of the disease.

Published in Stem Cell Research

ISSN: 1873-5061 (Print); 1876-7753 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Science: Biology (General)
Website: https://www.journals.elsevier.com/stem-cell-research

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