JMIR Public Health and Surveillance (Jun 2024)

U-Shaped Relationship Between Fibrinogen Level and 10-year Mortality in Patients With Acute Coronary Syndrome: Prospective Cohort Study

  • Yi ming Li,
  • Yuheng Jia,
  • Lin Bai,
  • Bosen Yang,
  • Mao Chen,
  • Yong Peng

DOI
https://doi.org/10.2196/54485
Journal volume & issue
Vol. 10
p. e54485

Abstract

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This study demonstrated that fibrinogen is an independent risk factor for 10-year mortality in patients with acute coronary syndrome (ACS), with a U-shaped nonlinear relationship observed between the two. These findings underscore the importance of monitoring fibrinogen levels and the consideration of long-term anti-inflammatory treatment in the clinical management of patients with ACS.