ctDNA and CTCs in Liquid Biopsy – Current Status and Where We Need to Progress

Abstract

We discuss the current status of liquid biopsy and its advantages and challenges with a focus on pre-analytical sample handling, technologies and workflows. The potential of circulating tumor cells and circulating tumor DNA is pointed out and an overview of corresponding technologies is given. Keywords: Liquid biopsy, Circulating tumor DNA, Circulating tumor cells, Pre-analytical handling, Technology overview