Molbank (Jun 2013)

N-(2-Chloro-5-cyanophenyl)-4,4,4-trifluorobutanamide

  • Tadimety Madhu Chakrapani Rao,
  • Govindaiah Shivaraja,
  • Swamy Sreenivasa,
  • Karikere Ekanna Manojkumar

DOI
https://doi.org/10.3390/M803
Journal volume & issue
Vol. 2013, no. 3
p. M803

Abstract

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N-(2-Chloro-5-cyanophenyl)-4,4,4-trifluorobutanamide (3) was synthesized by reacting 4,4,4-trifluorobutanoic acid (1) with 2-amino-4-chlorobenzonitrile (2) in the presence of triethylamine and propylphosphonic anhydride in ethyl acetate. Character­ization of the compound was done by IR, 1H-NMR, 13C-NMR, LC-MS and CHN analysis.

Keywords