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Disease Models & Mechanisms
(Mar 2023)
Activated PI3K delta syndrome 1 mutations cause neutrophilia in zebrafish larvae
Stone Elworthy,
Holly A. Rutherford,
Tomasz K. Prajsnar,
Noémie M. Hamilton,
Katja Vogt,
Stephen A. Renshaw,
Alison M. Condliffe
Affiliations
Stone Elworthy
Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield S10 2TN, UK
Holly A. Rutherford
Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield S10 2TN, UK
Tomasz K. Prajsnar
Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield S10 2TN, UK
Noémie M. Hamilton
Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield S10 2TN, UK
Katja Vogt
Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield S10 2TN, UK
Stephen A. Renshaw
Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield S10 2TN, UK
Alison M. Condliffe
Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield S10 2TN, UK
DOI
https://doi.org/10.1242/dmm.049841
Journal volume & issue
Vol. 16, no. 3
Abstract
Read online
No abstracts available.
Keywords
apds
zebrafish
pi3k delta
homology-directed gene editing
crispr
cas12a
cpf1
neutrophil
neutrophilia
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